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Research: BANERJEE and colleagues,
Listed in Issue 46
Abstract
BANERJEE and colleagues, Department of Occupational Health, All India Institute of Hygiene & Public Health, Calcutta India write that free radicals and lipid peroxidation play a significant role in the causation of human disease such as cancer, atherosclerosis, rheumatoid, arthritis, cataract by oxidative damage and functional degeneration of the tissues. The authors conducted a study to study the effect of cigarette smoking upon Vitamin C, glutathione and lipid peroxidation status .
Background
Methodology
Results
Vitamin C and other antioxidants such as glutathione protect the lipids of lipoproteins and other biomembranes against peroxidative damage. Cigarette smoking affected vitamin Cs and glutathiones antioxidant protective action. The group of adult male smokers in this study were found to have lowered vitamin C and glutathione levels and increased lipid-peroxide levels in their blood.
Conclusion
The increased pathogenicity of the smoking may also be due to indirect biochemical effect of enhanced oxidative stress by increased lipid-peroxidation and lowered vitamin C and other antioxidants at tissue level.
References
Banerjee KK et al. Influence of cigarette smoking on Vitamin C, glutathione and lipid peroxidation status. Indian Journal of Public Health 42(1): 20-3. Jan-Mar 1998.
