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Research: BLOEDON and SZAPARY,
Listed in Issue 100
Abstract
BLOEDON and SZAPARY, School of Nursing, The Center for Experimental Therapeutics, Division of General Internal Medicine, University of Pennsylvania, Philadelphia, PA 19104-6021, USA, have reviewed (75 references) flaxseed and cardiovascular risk. Abstract: Flaxseed, or linseed, is the richest known source of alpha-linoleic acid as well as the phytooestrogen, lignans. It is also a good source of soluble fibre. Studies have shown that flaxseed can reduce total serum lipoprotein, low-density lipoprotein, cholesterol concentrations, postprandial glucose absorption, and some markers of inflammation. It raises serum levels of the n-3 fatty acids alpha-linoleic acid and eicosapentaenoic acid. However data on antiplatelet, antioxidant, and hypotensive effects of flaxseed are inconclusive, and such activities would have to be demonstrated for flaxseed to be good protector against cardiovascular risk. More research is therefore needed in order to establish the role of flaxseed in the prevention of cardiovascular disease.
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References
Bloedon LT, Szapary PD. Flaxseed and cardiovascular risk. Nutrition reviews 62 (1): 18-27, Jan 2004.