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Research: CAMARGO and colleagues, D
Listed in Issue 28
Abstract
CAMARGO and colleagues, Division of Preventive Medicine, Brigham and Women's Hospital, Boston MA USA camargoc@al.mgh.harvard.edu write that moderate alcohol consumption decreases the risk of coronary heart disease, but that its effect upon peripheral arterial disease (PAD) is as yet unknown. The authors studied the relationship between moderate alcohol consumption and risk of PAD. @m: Within the Physicians' Health Study, which was a randomised trial studying the use of aspirin and beta carotene in over 22,000 apparently healthy men, the authors documented 433 incident cases of PAD during the 11 years of follow-up. @r: After controlling for age and treatment assignment, daily drinkers (> or = 7 drinks per week) had a relative risk (RR) of PAD of 0.92, compared to the reference group (<1 drink weekly). Following further control for smoking, however, the RR was 0.68 and with further control for exercise, diabetes mellittus, and family history of heart attack revealed an RR of 0.74. @c:CONCLUSIONS: Moderate alcohol consumption appears to decrease risk of PAD in apparently healthy men.
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References
Camargo CA Jr et al. Prospective study of moderate alcohol consumption and risk of peripheral arterial disease in US male physicians. Circulation 95(3): 577-80. Feb 4 1997.