Research: CHAN and colleagues, G

Listed in Issue 33

Abstract

CHAN and colleagues, Graduate Institute of Pharmaceutical Chemistry, China Medical College, Taichung, Taiwan, Republic of China isolated three new flavonoids, together with twenty-two known compounds, from the heartwood of Dalbergia odorifera T. Chen (Leguminosae).

Background

Methodology

These flavonoids were evaluated in antiallergic and anti- inflammatory tests.

Results

The results indicated that (S)-4-methoxydalbergione (1) and cearoin (2) exhibited antiallergic activity and that (S)-4-methoxydalbergione (1), cearoin (2), butein (13), koparin (15), bowdichione (16), 3-O-methylviolanone (23), and xenognosin B (24) demonstrated significant anti-inflammatory activity.

Conclusion

References

Chan SC et al. Three new flavonoids and antiallergic, anti-inflammatory constituents from the heartwood of Dalbergia odorifera. Planta Med 64(2): 153-8. Mar 1998.

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