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Research: COLLIS and colleagues,
Listed in Issue 52
Abstract
COLLIS and colleagues, Department of Plastic Surgery, Bradford Royal Infirmary, West Yorkshire, England UK. nicollis@aol.com write that cellulite is a common phenomenon particularly affecting the thighs and buttocks of women, and that there is little scientific evidence supporting any of the many advertised treatments. The authors conducted a randomized controlled trial to assess the effectiveness of two cellulite treatments .
Background
Methodology
52 out of 69 women, divided into three groups, completed a 12-week, randomized controlled trial. Patients acted as their own controls. Treatments investigated were twice-daily application of aminophylline cream and twice-weekly treatment with Endermologie ESI. Group 1 (double blind) received aminophylline to one thigh/buttock and a placebo cream to the other. Group 2 (singly blind) received Endermologie to one thigh/buttock. Group 3 received Endermologie to both sides and used the same cream regimen as group 1. Results were assessed subjectively by the patient and by clinical examination and photographic assessment by the surgeon before and after the trial. Morphologic assessment included body mass index, thigh girth at two points, and thigh fat depth measurement by ultrasound.
Results
No statistical difference were detected in measurements between legs for any of the treatment groups. The best subjective assessment by the patients themselves, revealed that only 3 of 35 aminophylline-treated legs and 10 of 35 Endermologie-treated legs had their cellulite appearance improved.
Conclusion
The authors do not believe that either of these two treatments is effective in improving the appearance of cellulite.
References
Collis N et al. Cellulite treatment: a myth or reality: a prospective randomized, controlled trial of two therapies, endermologie and aminophylline cream. Plastic and Reconstructive Surgery 104(4): 1110-4. Sep 1999.
