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Research: COTT and colleagues, A
Listed in Issue 41
Abstract
COTT and colleagues, Adult Psychopharmacology Program, National Institute of Mental Health, Rockville, Maryland 20857, USA write that St Johns wort (Hypericum perforatum) is a remarkably safe antidepressant with an apparently unique mode of action . St Johns wort has demonstrated efficacy with mild and moderate depression when compared with placebo or tricyclic antidepressants,; however there is scope for further research areas to be explored. These areas include a comparison of St Johns worts effects with serotonin reuptake inhibitors. Additionally, there do not appear to be any studies with severely depressed patients, or studies regarding its utility as a therapeutic adjunct to standard antidepressants.
Background
Methodology
Results
Conclusion
References
Cott JM and Fugh-Berman A. Is St Johns wort (Hypericum perforatum) an effective antidepressant? J Nerv Ment Dis 186(8): 500-1 Aug 1998.
