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Research: COYLE, Department of Neur
Listed in Issue 21
Abstract
COYLE, Department of Neurology, Health Sciences Center, State University at New York (SUNY), Stony Brook USA writes that the aim of this clinical review (83 references) is to highlight recent advances in immunology and information from selected other fields which have resulted in a better appreciation of neuroimmunological mechanisms involved in Multiple sclerosis (MS). New research information regarding immunopathology, the cytokine network and the role of oligodendrocytes, lymphocytes and endothelial cells in MS have resulted in new therapeutic approaches. Additionally, new information regarding clinical course and neuroimaging disease features and the role of genetic factors and infectious agents have improved the understanding of the immune basis for MS.
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References
Coyle PK. The neuroimmunology of multiple sclerosis. Adv Neuroimmunol. 6(2): 143-54. 1996.