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Research: DUDDUKURI and colleagues,
Listed in Issue 37
Abstract
DUDDUKURI and colleagues, Department of Biochemistry, Andhra University, Visakhapatnam, Andhra Pradesh, India studied the immunomodulatory activity of honey.
Background
Methodology
The authors investigated the induction of murine humoral antibody responses against various allergens using passive cutaneous anaphylaxis and Ouchterlony double immunodiffusion techniques.
Results
Ovalbumin (OVA)-specific IgE antibody responses with varying doses were completely suppressed by a number of sources of commercial honeys. Honey also suppressed the induction of OVA-specific humoral antibody responses in a number of strains of mice.
Conclusion
These results confirm the immunosuppressive activity of honey and suggest its possible application to health conditions requiring immunosuppression .
References
Duddukuri GR et al. Immunosuppressive effect of honey on the induction of allergen-specific humoral antibody response in mice. Int Arch Allergy Immunol 114(4): 385-8. Dec 1997.
