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Research: EGGER and colleagues, Sch
Listed in Issue 55
Abstract
EGGER and colleagues, School of Health Sciences, Deakin University, Melbourne, Victoria, Australia. eggergj@ozemail.com.au review the evidence (69 references) regarding the effectiveness of non-prescription weight loss supplements.
Background
Methodology
The authors conducted a detailed literature search including all relevant medical and supplementary databases and evidence from manufacturers. The authors considered the theoretical basis and rationale regarding each substance, as well as available research regarding its efficacy and potential risks. The level of evidence was classified according to the main research studies for each substance.
Results
There was no good evidence for weight loss benefits from most of the substances reviewed by the authors; however there was evidence supporting mild effects of capsaicin, caffeine and fibre, but only in whole foods. In certain cases, e.g. chitosan there is a plausible theoretical basis for the product, but no supporting proof of effect in humans in the absence of a calorie-controlled diet. Potential synergistic effects of different ingredients cannot be dismissed, but cant be assessed from current data.
Conclusion
There is an absence of good quality research regarding many substances, which means that advertising claims may be misleading.
References
Egger G et al. The effectiveness of popular, non-prescription weight loss supplements. The Medical Journal of Australia 171(11-12): 604-8. 6-20 Dec 1999.
