Research: ELATTAR and VIRJI,

Listed in Issue 43

Abstract

ELATTAR and VIRJI, Hormone Research Laboratory, University of Missouri-Kansas City, School of Dentistry 64108 USA researched the effect of treating human tongue cancer cells with vitamin E .

Background

Methodology

The authors treated human tongue squamous carcinoma cell SCC-25 with physiological concentrations of vitamin E succinate (VES), varying from 0.001 to 50 micromoles/L.

Results

Treatment with vitamin E in concentrations of 0.001 to 50 micromoles/L resulted in significant dose-dependent stimulation of cell growth, whereas pharmacological doses of vitamin E (100-154 micromoles/L) induced significant inhibition of cell growth.

Conclusion

References

Elattar TM and Virji AS Biphasic action of vitamin E on the growth of human oral squamous carcinoma cells. Anticancer Research 19(1A): 365-8. Jan-Feb 1999.

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