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Research: EVSTIGNEEVA and colleague
Listed in Issue 42
Abstract
EVSTIGNEEVA and colleagues, Lomonosov Moscow State Academy of Fine Chemical Technology, rpe@httos.mitht.msk.ru reviews the known literature (150 references) regarding the mechanisms of molecular action of vitamin E in biological membrane systems .
Background
Methodology
Results
Vitamin E possesses a broad range of biological activities. It acts as a universal stabiliser of biological membranes in normal oxygen metabolism and peroxidation and in disorders of normal metabolism resulting in pathological alterations. The author considers how Vitamin E participates in redox reactions in liquid media, its interaction with singlet oxygen, free fatty acids and enzyme systems. Also covered are the physiological effects of vitamin E and its ability to prevent numerous pathologies.
Conclusion
Vitamin E is a universal participant of antioxidant defence reactions in biological membranes; it acts at all stages of membrane oxidative damage.
References
Evstignneeva RP et al. Vitamin E as a universal antioxidant and stabilizer of biological membranes. Membr Cell Biol 12(2): 151-72. 1998.
