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Research: HAKKAK and colleagues,
Listed in Issue 67
Abstract
HAKKAK and colleagues, Arkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, 1120 Marshall Street, Little Rock, AR, USA, hakkakreza@uams.edu, examined the effect of two different sources of dietary protein on the formation of colonic tumours in rats.
Background
Diet, and in particular the kinds of protein that we ingest, has been implicated in the aetiology of colon cancer .
Methodology
In this controlled study, rats were fed life-long on a formulated diet containing only protein from either cow milk (casein) or from soybean . The rats under study were also treated with a carcinogenic agent, azoxymethane, for a period of 40 weeks, before being sacrificed. Post-mortem examination of their colons was then performed.
Results
Rats fed on a casein diet had a 50% incidence of colon tumours, as compared with 12% of rats fed on soy protein (p = 0.05).
Conclusion
The result suggests that consumption of soy protein may reduce the risk of developing colon cancer .
References
Hakka R, Korourian S, Ronis MJ, Johnston JM, Badger TM. Soy protein isolate consumption protects against azoxymethane-induced colon tumours in male rats. Cancer Letters 166 (1): 27-32. May 2001.
