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Research: HEINECKE, Departments
Listed in Issue 78
Abstract
HEINECKE, Departments of Medicine and Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO, USA, heinecke@im.wustl.edu, reviewed (44 references) evidence for a role of oxidized low-density lipoprotein (LDL) in atherosclerosis and the ability of vitamin E to augment antioxidant defence in humans.
Background
Methodology
Results
Conclusion
References
Heinecke JW. Is the emperor wearing clothes? Clinical trials of vitamin E and the LDL oxidation hypothesis. Arteriosclerosis, Thrombosis and Vascular Biology 21 (8): 1261-4. Aug 2001.
Comment
More definitive clinical studies, using dose regimens of vitamin E that have been shown to effectively inhibit lipid peroxidation in humans, would seem warranted.
