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Research: KIECOLT-GLASER and collea
Listed in Issue 74
Abstract
KIECOLT-GLASER and colleagues, Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210, USA, kiecolt-glaser.1@osu.edu, analysed the effects of hypnotic-relaxation training on cellular immune function during a stressful event .
Background
Methodology
Subjects were 33 medical and dental students, selected according to their hypnotic susceptibility. Blood samples were taken during a 'lower stress' period and again 3 days before their first major exam of the term. Half of subjects were randomly assigned to receive hypnotic-relaxation training in the period between blood sampling.
Results
Control subjects showed stress-related decreases in immune cell proliferative responses to two mitogens and percentages of CD3+ and CD4+ T-lymphocytes and interleukin-1 production by peripheral blood leukocytes. Subjects who underwent hypnosis-relaxation were, on average, protected from these immunological changes . More frequent hypnotic-relaxation practice resulted in higher percentages of CD3+ and CD4+ T-lymphocytes.
Conclusion
The results provide encouraging evidence that hypnosis- relaxation can reduce detrimental immune function changes associated with acute stress .
References
Kiecolt-Glaser JK et al. Hypnosis as a modulator of cellular immune dysregulation during acute stress. Journal of Consulting and Clinical Psychology 69 (4): 674-82. Aug 2001.
