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Research: KWASNIEWSKA and colleague
Listed in Issue 32
Abstract
KWASNIEWSKA and colleagues, I Clinic of Obstetrics and Gynaecology, Lublin Medical Academy, Poland studied the level of alpha-tocopherol (vitamin E) in the blood serum of female patients infected with the human Papillomavirus (HPV) with cervical dysplasias.
Background
Methodology
Levels of alpha-tocopherol were determined in 228 women with a normal cytological smear and 342 patients with cervical intraepithelial neoplasia (CIN). Using the HPV digene hybrid capture system enabled the authors to identify and distinguish HPV-negative patients with a normal Pap smear from HPV-positive patients with CIN.
Results
There was a statistically significantly lower level of alpha-tocopherol in the blood serum of HPV-positive patients with CIN compared to the HPV-negative women. Risk of dysplasia was 4 x higher for alpha-tocopherol levels <7.95 mumol/l.
Conclusion
References
Kwasniewska A et al. Content of alpha-tocopherol in blood serum of human Papillomavirus-infected women with cervical dysplasias. Nutr Cancer 28(3): 248-51. 1997.
