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Research: LEE and LIP,
Listed in Issue 96
Abstract
LEE and LIP, Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK, have reviewed (98 references) the literature on the role of n-3 fatty acids in the prevention of cardiovascular disease. Abstract: The benefits of fatty fish consumption have been explored in cell culture and animal studies, as well as in randomized controlled trials investigating the cardioprotective effects of n-3 fatty acids. Dietary n-3 fatty acids appear to stabilize the myocardium electrically, thereby reducing the risk of ventricular arrhythmias and sudden death. They also have potent anti-inflammatory effects and may be antithrombotic and anti-atherogenic. A recent study of 11,324 patients showed a marked decrease in sudden cardiac death and a reduction in all-cause mortality in the group taking a highly purified form of n-3 fatty acids. The use of n-3 fatty acids should be considered as part of secondary prevention strategies post-myocardial infarction.
Background
Methodology
Results
Conclusion
References
Lee KW, Lip GYH. The role of omega-3 fatty acids in the secondary prevention of cardiovascular disease. QJM 96 (7): 465-480, Jul 2003.
