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Research: LIU et al., Foo
Listed in Issue 85
Abstract
LIU et al., Food Engineering Research Center of State Education Ministry, Zhongshan University, Guangzhou 510275, People's Republic of China, found antitumour activity of germinating spores of Ganoderma luicidum .
Background
To investigate a potential anticancer agent .
Methodology
The inhibitory effects of dormant spores, germinating spores, sporoderm-broken germinating spores, and lipids extracted from the germinating spores of the fungus Ganoderma lucidum on the growth of mouse hepatoma, sarcoma S-180, and reticulocyte sarcoma L-II cells were measured.
Results
The sporoderm-broken spores showed much higher antitumour activity than whole spores. Lipid extracts had remarkable antitumour effects and inhibited three tumours with an inhibition of 89–90%.
Conclusion
References
Liu X, Yuan JP, Chung CK, Chen XJ. Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum. Cancer Letters 182 (2): 155-161, Aug 2002.
