Positive Health Online

Abstract

MACGREGOR and co-authors, Beatson Oncology Centre, Western Infirmary, Dumbarton Road, Glasgow G11 5NT, Scotland, UK, have tested soy supplements for the treatment of menopausal symptoms in women with early breast cancer.

Background

Menopausal symptoms are a major issue for patients with for breast cancer. There are increasing concerns over the use of hormone replacement therapy (HRT) in this setting and a growing consumer interest in 'natural' therapies. It has been suggested that soy phyto-oestrogens might be beneficial in the treatment of menopausal symptoms.

Methodology

72 patients with a diagnosis of breast cancer who were having menopausal symptoms were randomized between 12 weeks of treatment with soy capsules or placebo. Quality of life and menopausal symptom scores were assessed at baseline, 4, 8 and 12 weeks.

Results

There was no statistical difference in menopausal symptom scores or quality of life between the two arms of the study.

Conclusion

This study does not support the use of soy supplements as oestrogen substitutes.

References

MacGregor CA, Canney PA, Patterson G, McDonald R, Paul J. A randomised double-blind controlled trial of oral soy supplements versus placebo for treatment of menopausal symptoms in patients with early breast cancer. European Journal of Cancer 41 (5): 708-714, Mar 2005.