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Research: MILDE and colleagues,
Listed in Issue 72
Abstract
MILDE and colleagues, Department of Analytical Chemistry, Palack University, Olomouc, Czech Republic, analysed levels of the trace elements selenium, manganese, copper and iron in blood serum from patients with colorectal cancer .
Background
Methodology
The study involved patients with adenocarcinoma colorectal cancer and age-matched control subjects from the Moravian region of the Czech Republic. The researchers used atomic absorption spectrometry with graphite furnace atomization to analyse selenium and manganese levels and with flame atomization to analyse copper and iron levels.
Results
Colorectal cancer patients had significantly lower serum selenium levels (41.811.6 g/L) and significantly higher serum manganese (16.34.5 g/L) and iron (2.891.23 mg/L) levels compared with controls. Serum copper levels in cancer patients (0.950.28 mg/L) did not differ significantly from those of controls.
Conclusion
References
Milde D et al. Serum levels of selenium, manganese, copper, and iron in colorectal cancer patients. Biological Trace Element Research 79 (2): 107-14. Feb 2001.
Comment
The above two studies suggest the potentially powerful role of minerals including selenium in the aetiology of a number of cancers.
