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Research: NAKAJI and colleagues,
Listed in Issue 85
Abstract
NAKAJI and colleagues, Department of Hygiene, Hirosaki University School of Medicine, Hirosaki 036-8562, Japan, nakaji@cc.hirosaki-u.ac.jp, investigate the relationship between mineral and trace element concentrations in drinking water and stomach cancer mortality in Japan.
Background
The incidence and mortality from gastric cancer in Japan are the highest in the world . This is thought to be connected to dietary habits, particularly a high salt intake . The relationship between mineral and trace element intake and gastric carcinogenesis is however poorly researched .
Methodology
Epidemiological study relating the concentrations of 14 elements in drinking water from 36 water treatment plants to the geographical distribution of gastric cancer mortality rates . Multiple regression analysis was performed.
Results
The relationship was found to be significant in men for zinc, lead, strontium, and selenium ; in women it was significant for lead, strontium, and gold .
Conclusion
It is suggested that selenium and zinc may act to prevent gastric cancer . However there was no significant relationship observed between sodium and gastric carcinogenesis, although other studies have suggested such a link.
References
Nakaji S, Fukuda S, Sakamoto J, Sugawara K, Shimoyama T, Umeda T, Baxter D. Relationship between mineral and trace element concentrations in drinking water and gastric cancer mortality in Japan. Nutrition and Cancer 40 (2): 99-102, 2001.
