Research: NAVARRETE and colleagues,

Listed in Issue 72

Abstract

NAVARRETE and colleagues, Faculty of Chemistry, Inorganic and Nuclear Chemistry Department, National University of Mexico, Mexico City, reported on a relationship between urinary selenium excretion and cervical uterine cancer .

Background

Methodology

The researchers developed a simple chemical method to concentrate trace amounts of selenium from relatively large urine samples by using small activated carbon filters. When the filters were irradiated with thermal neutrons, selenium could be determined either by 77 mSe (t½ = 17.5 seconds) or 75 Se (t½ = 120 days). This article reported the results of 82 urine samples from women with cervical uterine cancer in several stages of development and from healthy controls.

Results

Urine samples from cervical cancer patients showed statistically significantly higher selenium levels than those from healthy controls. Urinary selenium excretion was highest for patients in the intermediate stages of cervical cancer.

Conclusion

References

Navarrete M et al. Urinary selenium excretion in patients with cervical uterine cancer. Biological Trace Element Research 79 (2): 97-105. Feb 2001.

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