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Research: OSAKA, and COLLEAGUES,
Listed in Issue 174
Abstract
Background
Some patients with advanced cancer make use of complementary therapies for the reduction of anxiety and stress. These patients can suffer distressing end-of-life symptoms, which conventional treatments might not relieve satisfactorily. Although previous studies have suggested that complementary therapies could be useful for reducing distress in patients with cancer, it has remained unclear whether these benefits are applicable at the end-of-life stage. The current study examined to validate salivary chromogranin A (CgA) as a biomarker for relieving stress by hand massage in terminally ill patients.
Methodology
The study group comprised 34 inpatients in palliative care units. Each of these patients received a 5-minute massage to the upper extremity. Before and after the massage, saliva samples were collected in order to measure the CgA levels.
Results
The brief hand massage appears to reduce levels of stress according to the salivary CgA (p < 0.05). In addition, we found statistically significant changes in patient satisfaction with hand massage.
Conclusion
Salivary CgA could potentially be used as a biomarker to measure relieving stress by hand massage in a palliative-care setting.
References
Osaka I, Kurihara Y, Tanaka K, Nishizaki H, Aoki S and Adachi I. Endocrinological evaluations of brief hand massages in palliative care. Journal of Alternative & Complementary Medicine. 15 (9): 981-5. Sep 2009