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Research: RAN and COLLEAGUES
Listed in Issue 288
Abstract
RAN and COLLEAGUES, 1 Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; 2 Department of Neurology, Nankai Hospital, Tianjin Academy of Integrative Medicine, Tianjin 300100, China; 3 Department of Research and Development, Hangzhou DeBuYou Health Technology Co. Ltd., Hangzhou, Zhejiang 310018, China; 4 College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; 5 Department of Chemical Engineering, University of Florida, Gainesville, Florida 32611, USA conducted a meta-analysis of 9 randomized controlled trials to investigate whether vitamin C is effective in the treatment of the common cold.
Background
To investigate whether vitamin C is effective in the treatment of the common cold.
Methodology
After systematically searching the National Library of Medicine (PubMed), Cochrane Library, Elsevier, China National Knowledge Infrastructure (CNKI), VIP databases, and WANFANG databases, 9 randomized placebo-controlled trials were included in our meta-analysis in RevMan 5.3 software, all of which were in English.
Results
In the evaluation of vitamin C, administration of extra therapeutic doses at the onset of cold despite routine supplementation was found to help reduce its duration (mean difference (MD) = -0.56, 95% confidence interval (CI) [-1.03, -0.10], and P = 0.02), shorten the time of confinement indoors (MD = -0.41, 95% CI [-0.62, -0.19], and P = 0.0002), and relieve the symptoms associated with it, including chest pain (MD = -0.40, 95% CI [-0.77, -0.03], and P = 0.03), fever (MD = -0.45, 95% CI [-0.78, -0.11], and P = 0.009), and chills (MD = -0.36, 95% CI [-0.65, -0.07], and P = 0.01).
Conclusion
Extra doses of vitamin C could benefit some patients who contract the common cold despite taking daily vitamin C supplements.
References
Li Ran 1 , Wenli Zhao 1 2 , Jingxia Wang 3 , Hongwu Wang 4 , Ye Zhao 3 5 , Yiider Tseng 5 , Huaien Bu 4. Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials
Biomed Res Int.;2018:1837634. doi: 10.1155/2018/1837634. eCollection 2018. Jul 5 2018.
