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Research: SALAZAR-MARTINEZ and col
Listed in Issue 85
Abstract
SALAZAR-MARTINEZ and colleagues, Center for Research in Population Health, National Institute of Public Health, Cuernavaca, Mexica, esalazar@correo.insp.mx, investigate nutritional determinants of ovarian cancer risk .
Background
In recent years, diet has been recognised as an important factor in the development of ovarian cancer even though results have not been consistent. This study evaluates dietary factors related to the risk of ovarian cancer in Mexican women .
Methodology
Case-control study in a Social Security hospital in Mexico City, evaluating 84 new cases of ovarian cancer and 629 controls . A validated questionnaire with 116 items about food intake was used. Analysis of nutrients was performed with the residual method adjusted for total energy intake and other predictor variables through logistic regression methods.
Results
The nutrients negatively associated with risk of ovarian cancer were retinol and vitamin D . Carbohydrates were positively associated with risk of ovarian cancer, whereas tortilla intake did not show any association with ovarian cancer.
Conclusion
The diet of the Mexican population is typically rich in carbohydrates as corn is the main energy source. Vitamins such as retinol and vitamin D were shown to be associated with ovarian cancer in a way that suggests they can act as protectants.
References
Salazar-Martinez E, Lazcano-Ponce EC, Gonzalez LLG, Escudero de los Rios P, Hernandez AM. Nutritional determinants of epithelial ovarian cancer risk: a case-control study in Mexico. Oncology 63 (2): 151-157, 2002.
