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Research: SUZUKI and colleagues,
Listed in Issue 100
Abstract
SUZUKI and colleagues, Psycho-Oncology Division, National Cancer Center Research Institute East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan, have investigated the connection between daily n-3 fatty acid intake and depression in patients with lung cancer.
Background
The aim of this study was to examine the association between daily n-3 fatty acid intake and depression in Japanese cancer patients.
Methodology
n-3 fatty acid intake was measured in 771 patients with newly diagnosed lung cancer using a food frequency questionnaire. The prevalence of depression was assessed by using the Hospital Anxiety and Depression (HAD) scale.
Results
No significant association between either eicosapentaenoic acid or docosahexaenoic acid intake and depression was found. However there was an association between alpha-linolenic acid intake and depression as well as total n-3 fatty acid intake and depression.
Conclusion
The study suggests that the two n-3 acids, eicosapentaenoic and docosahexaenoic acids, are not linked to depression in cancer patients, but the total intake of n-3 fatty acids, and also the intake of alpha-linolenic acid may well be associated with less depression in cancer patients.
References
Suzuki S, Akechi T, Kobayashi M, Taniguchi K, Goto K, Sasaki S, Tsugane S, Nishiwaki Y, Miyaoka H, Uchitomi Y. Daily omega-3 fatty acid intake and depression in Japanese patients with newly diagnosed lung cancer. British Journal of Cancer 90 (4): 787-793, Feb 2004.
