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Research: VISIOLI and HAGEN,
Listed in Issue 155
Abstract
VISIOLI and HAGEN, UMR 7079, Universite' Paris 6 Pierre et Marie Curie, 7 quai saint Bernard, Batiment A, 5eme etage, 75005 Paris, France. francesco.visioli@snv.jussieu.fr review [97 References] the known effects of micronutrients on the ageing heart and propose strategies for dietary improvements.
Background
Methodology
Diet, along with genetic and environmental factors, is considered a major aspect affecting longevity as well as vascular disease outcome. Yet, inadequate nutritional intake is rampant among the elderly, affecting nearly 44% of otherwise healthy, community-dwellers in developed countries. Thus, malnutrition, both in quali- and quantitative terms and especially as related to micronutrient intake, may exacerbate intrinsic cardiovascular maladaptation associated with aging, affecting vascular disease outcomes as well as longevity.
Results
Conversely, there is accumulating evidence that diets enriched in micronutrients, including vitamins, polyphenols, and essential fatty acids, maintain cellular antioxidant status and stress response enzymes, which otherwise decrease with age.
Conclusion
Adequate intakes of micronutrients, either consequent to a correct diet or through supplementation, might afford the elderly protection from cardiovascular diseases.
References
Visioli F and Hagen TM. Nutritional strategies for healthy cardiovascular aging: focus on micronutrients. Pharmacological Research. 55(3): 199-206. Mar 2007.