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Research: WHANGER,
Listed in Issue 99
Abstract
WHANGER, Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA, phil.whanger@orst.edu, has reviewed (174 references) and updated the relationship between Selenium and cancer. Abstract: Selenium occurs in metabolizable form in cereal grains, yeast, and plants such as garlic and broccoli. Epidemiological studies have shown an inverse relationship between Selenium intake and the incidence of cancer. Levels of Selenium in blood are usually lower in patients with cancer, but there are more inconsistent results if Selenium levels are measured in toenails. 7 trials with human subjects, and about 100 studies with small animals, show a positive influence of Selenium on cancer prevention and reduction. Several mechanisms have been proposed whereby Selenium reduces tumours. The compound Se-methylselenocysteine (SeMCYS) is the form of Selenium in edible plants. It has been found to be the most effective form of the trace element in breast cancer reduction but perhaps not in the reduction of colon cancer.
Background
Methodology
Results
Conclusion
References
Whanger PD. Selenium and its relationship to cancer: an update dagger. The British Journal of Nutrition 91 (1): 11-28, Jan 2004.
