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Research: WILKINSON and CHODAK,
Listed in Issue 92
Abstract
WILKINSON and CHODAK, Midwest Prostate and Urology Health Center, Weiss Memorial Hospital, Chicago, IL 60640, USA, simonwilkinson@hotmail.com, have compiled a critical review (153 references) of complementary therapies for prostate cancer. Abstract: Relatively little is known about the aetiology of prostate cancer, and research into treatment lags behind research in to treatment of other common cancers. However the popularity of complementary treatments is growing. This article provides a critical review of recent evidence for dietary modifications, food supplements, and herbal treatments in prostate cancer prevention and treatment. Despite encouraging data for some of these interventions, it is generally agreed that only randomized controlled trials can produce the basis for universal guidelines. Such trials are complex and require lengthy follow-up periods. Until the data are available, health care professionals need to improve their knowledge and understanding of the current evidence for or against complementary therapies in prostate cancer.
Background
Methodology
Results
Conclusion
References
Wilkinson S, Chodak GW. Critical review of complementary therapies for prostate cancer. Journal of Clinical Oncology 21 (11): 2199-2210, Jun 2003.
Comment
What a catch-22 we are in regarding cancer research. Whenever positive clinical evidence emerges regarding nutritional or dietary approaches, it is never enough, because it isn't in the form of a long-term randomized control trial, which the authors acknowledge are complex and must be followed up for lengthy periods. Humans are not rats; they cannot be fed rigidly controlled diets and kept in cages to standardize their environmental exposure to carcinogens and other toxic substances. What we don't lack, however, is a large population of cancer patients, which could be randomized into trials testing various dietary regimes and supplements, herbal medicines, stress control programmes, etc. The cancer equivalent of the Dean Ornish Heart disease programs. How many more tens of thousands of cancer deaths will be have to suffer before we start using the nutritional and other substances we already have.
