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Research: WU and colleagues, First
Listed in Issue 25
Abstract
WU and colleagues, First Affiliated Hospital, West China University of Medical Sciences, Chengdu, China studied the role of acupuncture in the regulation of cellular immune function.
Background
Methodology
40 patients with malignant tumours were divided randomly into 2 groups of 20 people each; one group was treated with acupuncture, the second a control. Changes of T lymphocyte subsets (CD3+, CD4+, CD8+ soluble interleukin-2 receptor [SIL-2 R] and beta-endorphin [beta-EP]) in peripheral blood of patients with malignant tumours were observed prior to and following acupuncture treatment in a double blind protocol.
Results
Acupuncture enhanced cellular immunity in patients with malignant tumours in the following ways: 1) increased percentage of T lymphocyte subsets CD3+, CD4+ and CD4+/CD8+ ratio and beta-EP levels; 2) decreased levels of SIL-2 R. Beta-EP and T lymphocyte subsets were positively correlated; beta-EP and SIL-2 R and T lymphocyte subsets and SIL-2 R were negatively correlated.
Conclusion
: Acupuncture affects immunomodulation. The authors discuss the acupuncture immunomodulation network and explore possible mechanisms for these effects.
References
Wu B et al. Effect of acupuncture on immunomodulation in patients with malignant tumors. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 16(3): 139-4. March 1996 .
